ISSN 1662-4009 (online)

ey0015.14-3 | Sow during infancy and reap later | ESPEYB15

14.3 Early life experience drives structural variation of neural genomes in mice

TA Bedrosian , C Quayle , N Novaresi , FH Gage

To read the full abstract: Science 2018;359:1395-1399Brain development and behavior are influenced by early life experiences, such as nutrients, stress, adversity and maternal care. While we believe the epigenome is the mediator, these authors investigated whether the genome itself of individual brain cells could be changed by environmental factors. A possible mechanism relies on mo...